Graduate Aptitude Test in Engineering (GATE) is one of the biggest national entrance exam for Engineering. Various IITs conduct this test every year for 24 different papers. Biotechnology is one among those papers for which thousands of students apply every year. It is also called as BT paper in GATE 2020. To qualify in the exam with good score, it is must that every applicant should be aware of the GATE syllabus for the paper they are appearing in. Here we will talk about the GATE Biotechnology Syllabus which is also called as BT syllabus and all about it for this academic year.
Gate Syllabus for Biotechnology 2020
This year IIT Delhi publishes the GATE syllabus for Biotechnology PDF for the reference of the applicants. By knowing the detailed syllabus of the BT, candidates can focus on the topics that are given in the syllabus and get prepared for the test. This does not waste their precious time too. GATE syllabus for BT will be different from that of the syllabus that they have pursued in their degree. Applicants should note this point and go through the syllabus atleast once before starting their preparation.
GATE 2020 syllabus for Biotechnology comprises of five different sections and they are, Engineering Mathematics, General Biotechnology, Recombinant DNA Technology, Plant and Animal Biotechnology, and Bioprocess Engineering and Process Biotechnology. However, these are not only the topics from which the questions will be asked in GATE BT paper. The paper also includes 10 different questions asked from the GA syllabus i.e., General Aptitude syllabus. Check complete exam pattern for the BT paper available here.
GATE BT Syllabus and Exam Pattern 2020
Knowing the exam pattern is important for the applicants of the GATE BT paper. This will help them know the distribution of the marks, number of questions asked etc. so that they can better prepare the topics for which more marks are awarded. This helps them score high.
- GATE Biotechnology paper consists of 65 questions in total.
- BT paper includes 10 questions from GA and 55 questions from BT.
- The BT paper will be for 100 marks.
- Duration of the GATE BT paper is 3 hours.
- BT question paper will have two types of questions i.e., MCQs and NATs.
- MCQs have negative marking for wrong answers i.e., for 1 mark question 1/3 will be negative mark and for 2 mark question 2/3 will be negative mark.
- No negative mark for wrong answers in NAT questions.
|1.||Engineering Mathematics||Linear Algebra: Matrices and determinants, Systems of linear equations, Eigen values and Eigen vectors. Calculus: Limit, continuity and differentiability, Partial derivatives, Maxima and minima, Sequences and series, Test for convergence, Fourier Series. Differential Equations: Linear and nonlinear first order ODEs, higher order ODEs with constant coefficients, Cauchy’s and Euler’s equations, Laplace transforms, PDE-Laplace, heat and wave equations. Probability and Statistics: Mean, median, mode and standard deviation, Random variables, Poisson, normal and binomial distributions, Correlation and regression analysis. Numerical Methods: Solution of linear and nonlinear algebraic equations, Integration of trapezoidal and Simpson’s rule, Single and multistep methods for differential equations.|
|2.||General Biotechnology||Biochemistry: Biomolecules-structure and functions; Biological membranes, structure, action potential and transport processes; Enzymes- classification, kinetics and mechanism of action; Basic concepts and designs of metabolism (carbohydrates, lipids, amino acids and nucleic acids) photosynthesis, respiration and electron transport chain; Bioenergetics
Microbiology: Viruses- structure and classification; Microbial classification and diversity(bacterial, algal and fungal); Methods in microbiology; Microbial growth and nutrition; Aerobic and anaerobic respiration; Nitrogen fixation; Microbial diseases and host-pathogen interaction
Cell Biology: Prokaryotic and eukaryotic cell structure; Cell cycle and cell growth control; Cell-Cell communication, Cell signaling and signal transduction
Molecular Biology and Genetics: Molecular structure of genes and chromosomes; Mutations and mutagenesis; Nucleic acid replication, transcription, translation and their regulatory mechanisms in prokaryotes and eukaryotes; Mendelian inheritance; Gene interaction; Complementation; Linkage, recombination and chromosome mapping; Extra chromosomal inheritance; Microbial genetics (plasmids, transformation, transduction, conjugation); Horizontal gene transfer and Transposable elements; RNA interference; DNA damage and repair; Chromosomal variation; Molecular basis of genetic diseases
Analytical Techniques: Principles of microscopy-light, electron, fluorescent and confocal; Centrifugation- high speed and ultra; Principles of spectroscopy-UV, visible, CD, IR, FTIR, Raman, MS,NMR; Principles of chromatography- ion exchange, gel filtration, hydrophobic interaction, affinity, GC,HPLC, FPLC; Electrophoresis; Microarray
Immunology: History of Immunology; Innate, humoral and cell mediated immunity; Antigen; Antibody structure and function; Molecular basis of antibody diversity; Synthesis of antibody and secretion; Antigen-antibody reaction; Complement; Primary and secondary lymphoid organ; B and T cells and macrophages; Major histocompatibility complex (MHC); Antigen processing and presentation; Polyclonal and monoclonal antibody; Regulation of immune response; Immune tolerance; Hypersensitivity; Autoimmunity; Graft versus host reaction.
Bioinformatics: Major bioinformatic resources and search tools; Sequence and structure databases; Sequence analysis (biomolecular sequence file formats, scoring matrices, sequence alignment, phylogeny);Data mining and analytical tools for genomic and proteomic studies; Molecular dynamics and simulations (basic concepts including force fields, protein-protein, protein-nucleic acid, protein-ligand interaction)
|3.||Recombinant DNA Technology||Restriction and modification enzymes; Vectors; plasmid, bacteriophage and other viral vectors, cosmids, Ti plasmid, yeast artificial chromosome; mammalian and plant expression vectors; cDNA and genomic DNA library; Gene isolation, cloning and expression ; Transposons and gene targeting; DNA labeling; DNA sequencing; Polymerase chain reactions; DNA fingerprinting; Southern and northern blotting; In-situ hybridization; RAPD, RFLP; Site-directed mutagenesis; Gene transfer technologies; Gene therapy|
|4.||Plant and Animal Biotechnology||Totipotency; Regeneration of plants; Plant growth regulators and elicitors; Tissue culture and Cell suspension culture system: methodology, kinetics of growth and, nutrient optimization; Production of secondary metabolites by plant suspension cultures; Hairy root culture; transgenic plants; Plant products of industrial importance
Animal cell culture; media composition and growth conditions; Animal cell and tissue preservation; Anchorage and non-anchorage dependent cell culture; Kinetics of cell growth; Micro & macro-carrier culture; Hybridoma technology; Stem cell technology; Animal cloning; Transgenic animals
|5.||Bioprocess Engineering and Process Biotechnology||Chemical engineering principles applied to biological system, Principle of reactor design, ideal and non-ideal multiphase bioreactors, mass and heat transfer; Rheology of fermentation fluids, Aeration and agitation; Media formulation and optimization; Kinetics of microbial growth, substrate utilization and product formation; Sterilization of air and media; Batch, fed-batch and continuous processes; Various types of microbial and enzyme reactors; Instrumentation control and optimization; Unit operations in solid-liquid separation and liquid-liquid extraction; Process scale-up, economics and feasibility analysis
Engineering principle of bioprocessing- Upstream production and downstream; Bioprocess design and development from lab to industrial scale; Microbial, animal and plant cell culture platforms; Production of biomass and primary/secondary metabolites; Biofuels, Bioplastics, industrial enzymes, antibiotics; Large scale production and purification of recombinant proteins; Industrial application of chromatographic and membrane based bioseparation methods; Immobilization of biocatalysts (enzymes and cells) for bioconversion processes; Bioremediation-Aerobic and anaerobic processes for stabilization of solid / liquid wastes
|6.||General Aptitude||Syllabus Link|
After preparing the GATE Syllabus for Biotechnology, applicants are also advised to revise the previous papers to get an idea on the types of questions asked as well as the difficulty level of the paper. So that candidates can better prepare for the GATE 2020. Also practice some mock tests before appearing for the test directly as it is computer based test and it could be new for you. This gives you relief from the tension and be alert while you answer. To know more about GATE 2020, bookmark ePostbag and visit regularly.